Yes, almost always.
Zoning permits authorize the use of a building or property as well as the construction of, or an addition to, a building.
A zoning permit is required before a building permit may be issued by Planning and Development Services of Kenton County.
Check out these application guides:
Additions to Existing Structures
Carports and Detached Garages
Change of Use and New Business Tenant
Driveways and Parking
Short Term Rentals
Subdivision Drawing Example
Apply for a right-of-way or encroachment permit
Tree mitigation and hillside development
Long-term and short-term rental licenses
Apply for a construction/building permit
Applying for an Occupational License